Monomethyl lithospermate

Cat. No.: IBDI-430736

Monomethyl lithospermate activates the PI3K/AKT pathway, which plays a protective role in nerve injury. Monomethyl lithospermate can improve the survival ability of SHSY-5Y cells, inhibit the breakdown of mitochondrial membrane potential (MMOP) and inhibit cell apoptosis. Monomethyl lithospermate also reduced the level of oxidative stress in the brain tissue of rats with middle artery occlusion (MCAO) and improved nerve damage in rats with ischemic stroke (IS).

Product Details

Target	Akt
Molecular Weight	552.48
Synonyms	Lithospermic acid monomethyl ester
SMILES	O=C(/C=C/C1=C2C(O[[email protected]@H]([[email protected]]2C(OC)=O)C3=CC(O)=C(O)C=C3)=C(O)C=C1)O[[email protected]](CC4=CC(O)=C(O)C=C4)C(O)=O
Structure Classification	Phenols>Polyphenols

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.