Cat. No.: IBDAK-620507
Size:
Online InquiryOverview
Assay Type | ELISA set |
Product Type | Macrophage / Inflamm. |
Range | 15.625 pg/ml - 1000 pg/ml |
Species Reactivity | Reacts with: Monkey |
Platform | Reagents |
Application | Sandwich ELISA |
Properties
Carrier Free | Yes |
Target
Function | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
Sequence Similarities | Belongs to the IL-1 family. |
Cellular Localization | Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
Domain | The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function. |
Storage & Handling
Storage | Store at +4°C. |
Storage Buffer | Constituent: 100% PBS |