Latrunculin A

Cat. No.: IBDI-430224

Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with Kds of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration.

Product Details

Target	Arp2/3 Complex
Molecular Weight	421.55
Appearance	Liquid
Synonyms	LAT-A
SMILES	O=C1SC[[email protected]@H]([[email protected]]2(O)O[[email protected]]3([H])CC[[email protected]](C)/C=C\C=C\CC/C(C)=C\C(O[[email protected]@](C3)([H])C2)=O)N1
Structure Classification	Antibiotics>Macrolide Antibiotics
Purity	≥97.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.