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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Isosilybin A

Cat. No.: IBDI-430276

Isosilybin A, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-κB-androgen receptor (AR) axis.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target Apoptosis
Molecular Weight 482.44
Appearance Solid
SMILES O=C1[[email protected]](O)[[email protected]@H](C2=CC=C(O[[email protected]](C3=CC=C(O)C(OC)=C3)[[email protected]@H](CO)O4)C4=C2)OC5=CC(O)=CC(O)=C15
Structure Classification Flavonoids>Flavanonols
Phenols>Polyphenols
Purity 99.51%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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