Cat. No.: IBDAK-620550
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| Assay Type | ELISA set |
| Product Type | Cell Type Markers |
| Range | 62.5 pg/ml - 4000 pg/ml |
| Species Reactivity | Reacts with: Human |
| Platform | Reagents |
| Application | Sandwich ELISA |
Properties
| Carrier Free | Yes |
Target
| Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
| Tissue Specificity | Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. |
| Sequence Similarities | Contains 3 UPAR/Ly6 domains. |
| Cellular Localization | Secreted and Cell membrane. |
Storage & Handling
| Storage | Store at +4°C. |
| Storage Buffer | Constituent: 100% PBS |