Cat. No.: IBDAK-620637
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Sample Type | Serum, Cell culture media, Hep Plasma, EDTA Plasma, Cit plasma |
Detection Method | Colorimetric |
Assay Type | Sandwich (quantitative) |
Assay Time | 1 h 30 min |
Assay Duration | One step assay |
Product Type | Secreted Molecules |
Sensitivity | 1.89 pg/ml |
Range | 7.81 pg/ml - 500 pg/ml |
Species Reactivity | Reacts with: Human |
Platform | Pre-coated microplate (12 x 8 well strips) |
Target
Function | Calcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus. Binds calcium, zinc and copper. Presence of zinc increases the affinity for calcium. Plays an important role in the inflammatory response. Interaction with AGER on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. |
Tissue Specificity | Monocytes and lymphocytes. |
Sequence Similarities | Belongs to the S-101 family. Contains 2 EF-hand domains. |
Storage & Handling
Storage | Store at +4°C. Please refer to protocols. |