Cat. No.: IBDAK-620755
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Assay Type | ELISA set |
Product Type | Chemokines |
Range | 1.25 pg/ml - 160 pg/ml |
Species Reactivity | Reacts with: Human |
Platform | Reagents |
Application | Sandwich ELISA |
Properties
Carrier Free | Yes |
Target
Function | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. |
Tissue Specificity | Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate. |
Sequence Similarities | Belongs to the intercrine beta (chemokine CC) family. |
Cellular Localization | Secreted. |
Storage & Handling
Storage | Store at +4°C. |
Storage Buffer | Constituent: 100% PBS |