Human LAMP2 ELISA Kit

Overview

Sample Type	Serum, Cell culture media, Hep Plasma, EDTA Plasma, Cit plasma, Cerebral Spinal Fluid
Detection Method	Colorimetric
Assay Type	Sandwich (quantitative)
Assay Time	1 h 30 min
Assay Duration	One step assay
Product Type	Secreted Molecules
Sensitivity	18.248 pg/ml
Range	46.875 pg/ml - 3000 pg/ml
Species Reactivity	Reacts with: Human, Monkey
Platform	Pre-coated microplate (12 x 8 well strips)

Target

Function	Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter-and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
Tissue Specificity	Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle. Isoform LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung, kidney and pancreas, very low in liver.
Sequence Similarities	Belongs to the LAMP family.
Cellular Localization	Cell membrane. Endosome membrane. Lysosome membrane. This protein shuttles between lysosomes, endosomes, and the plasma membrane.

Storage & Handling

Storage

Store at -20°C. Please refer to protocols.