Cat. No.: IBDAK-620802
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| Detection Method | Colorimetric |
| Assay Type | ELISA set |
| Product Type | TLR Signaling |
| Sensitivity | 46.8 pg/ml |
| Range | 250 pg/ml - 16000 pg/ml |
| Species Reactivity | Reacts with: Human |
| Platform | Reagents |
| Application | ELISA |
Target
| Function | Required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1. |
| Sequence Similarities | Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily. Contains 1 death domain. Contains 1 protein kinase domain. |
Storage & Handling
| Storage | Store at +4°C. |
| Storage Buffer | Constituent: 100% PBS |