Cat. No.: IBDAK-620819
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Sample Type | Cell culture supernatant, Serum, Plasma |
Detection Method | Colorimetric |
Assay Type | Sandwich (quantitative) |
Assay Time | 2 h 15 min |
Assay Duration | Multiple steps standard assay |
Product Type | Chemokines |
Sensitivity | < 12.3 pg/ml |
Range | 31.25 pg/ml - 1000 pg/ml |
Species Reactivity | Reacts with: Human |
Platform | Microplate |
Target
Function | IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. |
Sequence Similarities | Belongs to the intercrine alpha (chemokine CxC) family. |
Cellular Localization | Secreted. |
Storage & Handling
Storage | Store at +4°C. Please refer to protocols. |