Human IL-18R1 ELISA Kit

Overview

Sample Type	Cell culture supernatant, Serum, Cell Lysate, Hep Plasma, EDTA Plasma, Tissue Homogenate
Detection Method	Colorimetric
Assay Type	Sandwich (quantitative)
Assay Time	3 h 30 min
Assay Duration	Multiple steps standard assay
Product Type	Macrophage / Inflamm.
Sensitivity	< 10 pg/ml
Range	31.2 pg/ml - 2000 pg/ml
Species Reactivity	Reacts with: Human
Platform	Pre-coated microplate (12 x 8 well strips)

Target

Function	Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B.
Tissue Specificity	Expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney. High level of expression in Hodgkin disease cell lines.
Sequence Similarities	Belongs to the interleukin-1 receptor family. Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 TIR domain.
Cellular Localization	Membrane.

Storage & Handling

Storage

Store at -20°C. Please refer to protocols.