Human ICAM1 ELISA Kit, Fluorescent

Overview

Sample Type	Cell culture supernatant, Serum, Cell culture extracts, Adherent cells, Tissue Extracts, Hep Plasma, EDTA Plasma, Cit plasma
Detection Method	Fluorescent
Assay Type	Sandwich (quantitative)
Assay Time	1 h 30 min
Assay Duration	One step assay
Product Type	Cell Type Markers
Sensitivity	2.4 pg/ml
Range	4.9 pg/ml - 20000 pg/ml
Species Reactivity	Reacts with: Human Does not react with: Goat, Cow, Pig
Platform	Pre-coated microplate (12 x 8 well strips)

Target

Function	ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Sequence Similarities	Belongs to the immunoglobulin superfamily. ICAM family. Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Cellular Localization	Membrane.

Storage & Handling

Storage

Store at +4°C. Please refer to protocols.