Human FABP2 ELISA Kit

Overview

Sample Type	Cell culture supernatant, Urine, Serum, Cell culture extracts, Hep Plasma, EDTA Plasma, Cit plasma
Detection Method	Colorimetric
Assay Type	Sandwich (quantitative)
Assay Time	1 h 30 min
Assay Duration	One step assay
Product Type	Redox Metabolism
Sensitivity	1.7 pg/ml
Range	12.5 pg/ml - 800 pg/ml
Species Reactivity	Reacts with: Human Does not react with: Cow
Platform	Pre-coated microplate (12 x 8 well strips)

Target

Function	FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
Tissue Specificity	Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.
Sequence Similarities	Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Cellular Localization	Cytoplasm.
Domain	Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.

Storage & Handling

Storage

Store at +4°C. Please refer to protocols.