Cat. No.: IBDAK-620969
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Sample Type | Cell culture supernatant, Cell Lysate, Hep Plasma, EDTA Plasma |
Detection Method | Colorimetric |
Assay Type | Sandwich (quantitative) |
Assay Time | 3 h 30 min |
Assay Duration | Multiple steps standard assay |
Product Type | Chemokines |
Sensitivity | < 10 pg/ml |
Range | 62.5 pg/ml - 4000 pg/ml |
Species Reactivity | Reacts with: Human |
Platform | Pre-coated microplate (12 x 8 well strips) |
Target
Function | Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactive for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays. |
Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte-derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes. |
Sequence Similarities | Belongs to the intercrine alpha (chemokine CxC) family. |
Cellular Localization | Secreted. |
Storage & Handling
Storage | Store at +4°C. Please refer to protocols. |