Cat. No.: IBDAK-620978
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Sample Type | Serum, Cell culture media, Hep Plasma, EDTA Plasma, Cit plasma |
Detection Method | Colorimetric |
Assay Type | Sandwich (quantitative) |
Assay Time | 1 h 30 min |
Assay Duration | One step assay |
Product Type | Secreted Molecules |
Sensitivity | 37 pg/ml |
Range | 46.88 pg/ml - 3000 pg/ml |
Species Reactivity | Reacts with: Human Does not react with: Cow |
Platform | Pre-coated microplate (12 x 8 well strips) |
Target
Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
Tissue Specificity | Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. |
Sequence Similarities | Belongs to the CCN family. Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 TSP type-1 domain. Contains 1 VWFC domain. |
Cellular Localization | Secreted > extracellular space > extracellular matrix. Secreted. |
Storage & Handling
Storage | Store at +4°C. Please refer to protocols. |