Cat. No.: IBDAK-620998
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| Sample Type | Cell culture supernatant |
| Detection Method | Colorimetric |
| Assay Type | Sandwich (quantitative) |
| Assay Time | 1 h 30 min |
| Assay Duration | One step assay |
| Product Type | Cell Type Markers |
| Sensitivity | 3.5 pg/ml |
| Range | 15.63 pg/ml - 1000 pg/ml |
| Species Reactivity | Reacts with: Human |
| Platform | Pre-coated microplate (12 x 8 well strips) |
Target
| Function | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. |
| Tissue Specificity | Expressed by activated B-lymphocytes and monocytes. |
| Sequence Similarities | Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
| Cellular Localization | Membrane. |
Storage & Handling
| Storage | Store at -20°C. Please refer to protocols. |