Cat. No.: IBDAK-621052
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Sample Type | Cell culture supernatant, Serum, Hep Plasma, Cit plasma |
Detection Method | Colorimetric |
Assay Type | Sandwich (quantitative) |
Assay Duration | Multiple steps standard assay |
Product Type | Cell Type Markers |
Sensitivity | 1.35 ng/ml |
Range | 1.311 ng/ml - 320 ng/ml |
Species Reactivity | Reacts with: Human |
Platform | Pre-coated microplate (12 x 8 well strips) |
Target
Function | Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
Tissue Specificity | Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts. |
Sequence Similarities | Contains 2 Ig-like C2-type (immunoglobulin-like) domains. |
Cellular Localization | Cell membrane. Secreted. Exists also as a soluble receptor. |
Storage & Handling
Storage | Store at +4°C. |
Storage Buffer | Constituent: 100% PBS |