Cat. No.: IBDAK-621078
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Assay Type | ELISA set |
Product Type | Chemokines |
Range | 3.44 pg/ml - 220 pg/ml |
Species Reactivity | Reacts with: Human |
Platform | Reagents |
Application | Sandwich ELISA |
Properties
Carrier Free | Yes |
Target
Function | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. |
Tissue Specificity | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. |
Sequence Similarities | Belongs to the intercrine beta (chemokine CC) family. |
Cellular Localization | Secreted. |
Storage & Handling
Storage | Store at +4°C. |
Storage Buffer | pH: 7.2 Constituent: 100% PBS |