Human C3/C3b Antibody Pair - BSA and Azide free

Overview

Assay Type	ELISA set
Product Type	Macrophage / Inflamm.
Range	15 pg/ml - 1000 pg/ml
Species Reactivity	Reacts with: Human
Platform	Reagents
Application	Sandwich ELISA

Properties

Carrier Free

Yes

Target

Function	C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Tissue Specificity	Plasma.
Sequence Similarities	Contains 1 anaphylatoxin-like domain. Contains 1 NTR domain.
Cellular Localization	Secreted.

Storage & Handling

Storage	Store at +4°C.
Storage Buffer	Constituent: 100% PBS