Human AGRP Antibody Pair - BSA and Azide free

Overview

Assay Type	ELISA set
Product Type	Redox Metabolism
Range	43.75 pg/ml - 2800 pg/ml
Species Reactivity	Reacts with: Human
Platform	Reagents
Application	Sandwich ELISA

Properties

Carrier Free

Yes

Target

Function	Plays a role in weight homeostasis. Plays a role in the central control of feeding. Reduces food intake. Inhibits cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Acts primarily on MC3R and MC4R. Has very low activity with MC5R.
Tissue Specificity	Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.
Sequence Similarities	Contains 1 agouti domain.
Cellular Localization	Secreted. Golgi apparatus lumen.
Domain	The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.

Storage & Handling

Storage	Store at +4°C.
Storage Buffer	Constituent: 100% PBS