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(-)-Epipodophyllotoxin

Cat. No.: IBDI-430859

(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum, with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro.

Size (Solid):

Product Details

Target Apoptosis
Molecular Weight 414.41
Appearance Solid
SMILES O=C1[[email protected]]([[email protected]]2([H])CO1)([H])[[email protected]@](C(C=C3OC)=CC(OC)=C3OC)([H])C4=CC(OCO5)=C5C=C4[[email protected]]2O
Structure Classification Phenylpropanoids>Lignans
Purity 99.85%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.