Cynaropicrin

Cat. No.: IBDI-430667

Cynaropicrin is a sesquiterpene lactone which can inhibit tumor necrosis factor (TNF-α) release with IC50s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively. Cynaropicrin also inhibits the increase of cartilage degradation factor (MMP13) and suppresses NF-κB signaling.

Product Details

Target	MMP | NF-κB | TNF Receptor
Molecular Weight	346.37
Appearance	Oil
SMILES	C=C([[email protected]]1O)[[email protected]]([[email protected]@]2([H])C1)([H])[[email protected]](OC3=O)([H])[[email protected]@](C3=C)([H])[[email protected]@H](OC(C(CO)=C)=O)CC2=C
Structure Classification	Phenols

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.