Cyclopamine

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Cat. No.: IBDI-430045

Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	Hedgehog \| Smo \| Endogenous Metabolite
Molecular Weight	411.62
Appearance	Solid
Synonyms	11-Deoxojervine
SMILES	CC1=C2[[email protected]@]([[email protected]@]3([H])[[email protected]]([[email protected]@]4(C(C[[email protected]@H](O)CC4)=CC3)C)([H])C2)([H])CC[[email protected]@]15[[email protected]@H]([[email protected]@]6([H])[[email protected]](C[[email protected]](C)CN6)([H])O5)C
Structure Classification	Alkaloids
Purity	99.97%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.