Corticosterone

Cat. No.: IBDI-430984

Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect.

Product Details

Target	Glucocorticoid Receptor | Endogenous Metabolite | iGluR
Molecular Weight	346.46
Appearance	Solid
Synonyms	17-Deoxycortisol, 11β,21-Dihydroxyprogesterone, Kendall's compound B
SMILES	C[[email protected]@]12[[email protected]@H](C(CO)=O)CC[[email protected]@]1([H])[[email protected]]3([H])CCC4=CC(CC[[email protected]]4(C)[[email protected]@]3([H])[[email protected]@H](O)C2)=O
Structure Classification	Steroids
Purity	99.70%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.