Claudin-18 Isoform 2 CHO Cell Line (High, Medium, or Low Expression)

Product Details

Synonyms	CLDN18, UNQ778, PRO1572, Claudin 18.2
Description	Recombinant clonal CHO cell line stably expressing full length human claudin 18.2 (claudin 18 isoform 2, CLDN 18.2, gene accession number NM_001002026.3). The stable clonal cell line was selected for different levels of Claudin 18.2 expression (High, Medium, and Low) compared to the parental CHO-K1 cell line.
Host Cell Line	CHO-K1 cells, Chinese Hamster Ovary, epithelial-like cells, adherent
Applications	• Test antibodies against Claudin 18.2 and anti-Claudin 18.2 CAR T cells for immunotherapy research and drug discovery. • Screen inhibitors or neutralizing antibodies against Claudin 18.2
Supplied As	Each vial contains 2 x 106 cells in 1 mL of cell freezing medium
Materials Required But Not Supplied	• Thaw Medium 3 • Growth Medium 3D
UniProt	P56856
Mycoplasma Testing	The cell line has been screened to confirm the absence of Mycoplasma species.
Scientific Category	Cell Signaling Pathway

Storage & Handling

Storage/Stability	Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.
Shipping Temperature	-80°C
Warnings	Avoid freeze/thaw cycles
Regulatory Status	Research Use Only