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Chicoric acid

Cat. No.: IBDI-430880

Chicoric acid (Cichoric acid), an orally active dicaffeyltartaric acid, induces reactive oxygen species (ROS) generation. Chicoric acid inhibits cell viability and induces mitochondria-dependent apoptosis in 3T3-L1 preadipocytes through ROS-mediated PI3K/Akt and MAPK signaling pathways. Chicoric acid increases glucose uptake, improves insulin resistance, and attenuates glucosamine-induced inflammation. Chicoric acid has antidiabetic properties and antioxidant, anti-inflammatory effects.

Size (Solution): 10 mM * 1 mL in Water

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target Reactive Oxygen Species | Apoptosis
Molecular Weight 474.37
Appearance Solid
Synonyms Cichoric acid, Dicaffeoyltartaric acid
SMILES O=C(O)[[email protected]](OC(/C=C/C1=CC=C(O)C(O)=C1)=O)[[email protected]@H](OC(/C=C/C2=CC=C(O)C(O)=C2)=O)C(O)=O
Structure Classification Phenylpropanoids>Other Phenylpropanoids
Phenols>Polyphenols
Purity 99.95%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.