- AminosalicylatesCorticosteroids for IBDCytokine-Targeted Therapies for IBDJanus Kinase Inhibitors for IBDDrugs Targeting Leukocyte Trafficking for IBDPPAR-γ Ligands for IBDAgents Targeting the TGF-β/Smad System in IBDMatrix Metalloproteinase Inhibitors for IBDImmunotherapies for IBDDrugs Targeting Toll-like Receptors in IBDS1P Receptor Modulators for IBD
- Antibiotic Therapies for IBDProbiotic Therapies for IBDFecal Microbiota Transplantation for IBDCell-based Therapies for IBD
- Drug Target Discovery for IBDLead Discovery for IBDLead Optimization for IBD
- In Vitro ADMEIn Vivo ADME TestingPharmacokinetic EvaluationBioanalysisMetabolite Profiling and IdentificationPreclinical Toxicology Studies for IBD DrugsIn Vitro Efficacy Testing for IBD Drugs
- Disease Activity Index AssessmentColon Length and Weight AssessmentColonoscopyHistology and Immunohistochemistry EvaluationInflammatory Marker AssessmentOxidative Stress Marker AssessmentIntestinal Permeability MeasurementImaging Services
- IBD Immunopathogenesis AnalysisGut Microbiota AnalysisGenetic Studies of IBDIntestinal Barrier Dysfunction in IBD
- Serum Biomarker Discovery for IBDSerological Biomarker Discovery for IBDInquiry
Assessment of Colon Length and Weight in IBD Animal Models
Shortening of the colon is one of the typical symptoms of colitis. Increased colon weight is also frequently observed due to edema, inflammatory cell infiltration and mucosal thickening in inflammatory bowel disease (IBD)animal models. Therefore, colon length and weight are key parameters in the evaluation of animal models of IBD. This parameter can be used as a quantitative measure of disease severity and to assess the efficacy of potential therapeutics.
Fig. 1. Colon length and weight of colitis mice. (Chen et al., 2017)
Our Colon Length and Weight Assessment Service
Ace Therapeutics is a research service provider in the field of IBD, providing reliable colon length and weight assessment services to pharmaceutical and biotech companies. Our team of experienced experts accurately measures the colon length and weight of IBD animals and provides data-driven analysis and interpretation.
Our services provide information about the severity of inflammation and tissue damage, as well as potential therapeutic effects. These measurements are relatively easy to obtain and can be used in conjunction with other histological and molecular analyses to provide a comprehensive understanding of the disease process.
- Morphological observation of colon in animals
- Colon length measurement in animals
- Calculation of colon weight to length ratio
Why Choose Us
- Professional services. We have an experienced team of professionals who can provide accurate and reliable colon length and weight assessment services.
- Advanced equipment. We are equipped with advanced equipment and technology that can ensure the accuracy and efficiency of the assessment process.
- Client needs. Our customized assessment solutions according to the needs and requirements of our clients to ensure that our services can best meet their needs.
- Timely communication. We provide timely communication and feedback, maintaining close contact with our clients to ensure smooth progress of our services.
With Ace Therapeutics' colon length and weight assessment service, researchers can more accurately assess the condition of animal models of IBD, providing more accurate data to support IBD research and drug development. If you need further information or would like to know more about our service, please feel free to contact us. We will be happy to provide you with support and assistance.
Reference
- Chen, X., et al. (2017). Prevent effects of Lactobacillus fermentum HY01 on dextran sulfate sodium-induced colitis in mice. Nutrients, 9(6), 545.
! For research use only, not intended for any clinical use.Related ServicesAssessment of Disease Activity Index (DAI) in IBD Animal Models Assessment of Inflammatory Markers in IBD Animal Models Assessment of Oxidative Stress Markers in IBD Animal Models Colonoscopy in IBD Animal Models Histological and Immunohistochemical Evaluation in IBD Animal Models Imaging Services in IBD Animal Models Measurement of Intestinal Permeability in IBD Animal Models
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