Apoptolidin

Cat. No.: IBDI-430583

Apoptolidin is a polyketide isolated from Nocardiopsis bacteria. Apoptolidin is a selective mitochondrial F1FO ATPase inhibitor. Apoptolidin is an apoptosis inducer and induces apoptotic cell death in cells transformed with the adenovirus type 12 oncogenes including ElA (IC50=10-17 ng/ml) but not in normal cells.

Product Details

Target	ATP Synthase | Apoptosis
Molecular Weight	1129.37
Appearance	Solid
SMILES	O[[email protected]]([[email protected]](OC(/C(C)=C/C(C)=C/C(C)=C/[[email protected]]1C)=O)([H])C[[email protected]@H]([[email protected]](CC/C=C(/C=C/[[email protected]]1O[[email protected]](O[[email protected]]2C)[[email protected]]([[email protected]@H]([[email protected]]2OC)O)O)C)O)OC)[[email protected]](O[[email protected]@H]([[email protected]@H]3C)C[[email protected]](COC)O[[email protected]](O[[email protected]]4C)C[[email protected]](O)([[email protected]]4O[[email protected]](O[[email protected]@H]5C)C[[email protected]]([[email protected]@H]5O)OC)C)([[email protected]@H]([[email protected]]3O)C)O
Structure Classification	Others
Purity	≥95.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.