Anti-TREM2 antibody - BSA and Azide free (Detector)

Overview

Product Type	Macrophage / Inflamm.
Host Species	Rabbit
Species Reactivity	Reacts with: Human
Application	Sandwich ELISA

Properties

Carrier Free	Yes
Clonality	Monoclonal
Conjugate	Unconjugated
Isotype	IgG

Target

Function	May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
Tissue Specificity	Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord.
Sequence Similarities	Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Cellular Localization	Secreted and Cell membrane.

Storage & Handling

Storage

Store at +4°C. Please refer to protocols.