Anti-SPON2 antibody - BSA and Azide free (Capture)

Overview

Product Type	Macrophage / Inflamm.
Host Species	Rabbit
Species Reactivity	Reacts with: Mouse, Rat, Human
Application	Sandwich ELISA

Properties

Carrier Free	Yes
Purity	Protein A purified
Clonality	Monoclonal
Conjugate	Unconjugated
Isotype	IgG

Target

Function	Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (By similarity). Binds bacterial lipopolysaccharide (LPS).
Tissue Specificity	Expressed in normal lung tissue but not in lung carcinoma cell lines.
Sequence Similarities	Contains 1 spondin domain. Contains 1 TSP type-1 domain.
Cellular Localization	Secreted > extracellular space > extracellular matrix.

Storage & Handling

Storage

Store at -20°C. Please refer to protocols.