Cat. No.: IBDAK-621307
Size:
Online InquiryOverview
| Product Type | Secreted Molecules |
| Host Species | Rabbit |
| Species Reactivity | Reacts with: Human |
| Application | Sandwich ELISA |
Properties
| Carrier Free | Yes |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Isotype | IgG |
Target
| Function | Calcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus. Binds calcium, zinc and copper. Presence of zinc increases the affinity for calcium. Plays an important role in the inflammatory response. Interaction with AGER on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. |
| Tissue Specificity | Monocytes and lymphocytes. |
| Sequence Similarities | Belongs to the S-101 family. Contains 2 EF-hand domains. |
Storage & Handling
| Storage | Store at +4°C. Please refer to protocols. |