Anti-RALBP1 antibody - BSA and Azide free (Detector)

Overview

Product Type	TLR Signaling
Host Species	Rabbit
Species Reactivity	Reacts with: Human
Application	Sandwich ELISA

Properties

Carrier Free	Yes
Clonality	Monoclonal
Conjugate	Unconjugated
Isotype	IgG

Target

Function	Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
Tissue Specificity	Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes.
Sequence Similarities	Contains 1 Rho-GAP domain.
Cellular Localization	Membrane.

Storage & Handling

Storage

Store at +4°C. Please refer to protocols.