Cat. No.: IBDAK-621325
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Product Type | Redox Metabolism |
Host Species | Rabbit |
Species Reactivity | Reacts with: Human |
Application | Sandwich ELISA |
Properties
Carrier Free | Yes |
Purity | Protein A purified |
Clonality | Monoclonal |
Conjugate | Unconjugated |
Isotype | IgG |
Target
Function | Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. |
Tissue Specificity | Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas. |
Sequence Similarities | Belongs to the paraoxonase family. |
Cellular Localization | Secreted > extracellular space. |
Storage & Handling
Storage | Store at +4°C. Please refer to protocols. |