Cat. No.: IBDAK-621378
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| Product Type | Chemokines |
| Host Species | Rabbit |
| Species Reactivity | Reacts with: Human |
| Application | Sandwich ELISA |
Properties
| Carrier Free | Yes |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Isotype | IgG |
Target
| Function | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. |
| Tissue Specificity | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. |
| Sequence Similarities | Belongs to the intercrine beta (chemokine CC) family. |
| Cellular Localization | Secreted. |
Storage & Handling
| Storage | Store at +4°C. Please refer to protocols. |