Cat. No.: IBDAK-621433
Size:
Online InquiryOverview
Product Type | Chemokines |
Host Species | Rabbit |
Species Reactivity | Reacts with: Human |
Application | Sandwich ELISA |
Properties
Carrier Free | Yes |
Clonality | Monoclonal |
Conjugate | Unconjugated |
Isotype | IgG |
Target
Function | Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15. |
Tissue Specificity | Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients. |
Sequence Similarities | Belongs to the intercrine beta (chemokine CC) family. |
Cellular Localization | Secreted. |
Storage & Handling
Storage | Store at -20°C. Please refer to protocols. |