Cat. No.: IBDAK-621514
Size:
Online InquiryOverview
| Product Type | Macrophage / Inflamm. |
| Host Species | Rabbit |
| Species Reactivity | Reacts with: Human |
| Application | Sandwich ELISA |
Properties
| Carrier Free | Yes |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Isotype | IgG |
Target
| Function | Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R. |
| Tissue Specificity | Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon. |
| Sequence Similarities | Belongs to the IL-34 family. |
| Cellular Localization | Secreted. |
Storage & Handling
| Storage | Store at +4°C. Please refer to protocols. |