Cat. No.: IBDAK-621555
Size:
Online InquiryOverview
| Product Type | Cell Type Markers |
| Host Species | Rabbit |
| Species Reactivity | Reacts with: Mouse |
| Application | Sandwich ELISA |
Properties
| Carrier Free | Yes |
| Purity | Protein A purified |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Isotype | IgG |
Target
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
| Sequence Similarities | Belongs to the immunoglobulin superfamily. ICAM family. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. |
| Cellular Localization | Membrane. |
Storage & Handling
| Storage | Store at +4°C. Please refer to protocols. |