Cat. No.: IBDAK-621580
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| Product Type | Secreted Molecules |
| Host Species | Rabbit |
| Species Reactivity | Reacts with: Mouse |
| Application | Sandwich ELISA |
Properties
| Carrier Free | Yes |
| Purity | Protein A purified |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Isotype | IgG |
Target
| Function | Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling.Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth. |
| Tissue Specificity | In myelogenous leukemic cell lines of promonocytic, promyelocytic, and proerythroid lineage, in fibroblasts, and very strongly in epithelial cell lines. Present in inflammatory cells and bone marrow. Highest levels in kidney. |
| Sequence Similarities | Belongs to the granulin family. |
| Cellular Localization | Secreted. |
Storage & Handling
| Storage | Store at +4°C. Please refer to protocols. |