Cat. No.: IBDAK-621602
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| Product Type | Secreted Molecules |
| Host Species | Rabbit |
| Species Reactivity | Reacts with: Human |
| Application | Sandwich ELISA |
Properties
| Carrier Free | Yes |
| Purity | Protein A purified |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Isotype | IgG |
Target
| Function | May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region. |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Sequence Similarities | Belongs to the ficolin lectin family. Contains 1 collagen-like domain. Contains 1 fibrinogen C-terminal domain. |
| Cellular Localization | Secreted. |
| Domain | The fibrinogen-like domain (FBG) contains potential calcium-binding sites that may be involved in carbohydrate binding. |
Storage & Handling
| Storage | Store at -20°C. Please refer to protocols. |