Cat. No.: IBDAK-621646
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Product Type | Chemokines |
Host Species | Rabbit |
Species Reactivity | Reacts with: Human |
Application | Sandwich ELISA |
Properties
Carrier Free | Yes |
Purity | Protein A purified |
Clonality | Monoclonal |
Conjugate | Unconjugated |
Isotype | IgG |
Target
Function | LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. |
Sequence Similarities | Belongs to the intercrine alpha (chemokine CxC) family. |
Cellular Localization | Secreted. |
Storage & Handling
Storage | Store at -20°C. Please refer to protocols. |