Cat. No.: IBDAK-621665
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| Product Type | Chemokines |
| Host Species | Rabbit |
| Species Reactivity | Reacts with: Human |
| Application | Sandwich ELISA |
Properties
| Carrier Free | Yes |
| Purity | Protein A purified |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Isotype | IgG |
Target
| Function | Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. |
| Tissue Specificity | Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow. |
| Sequence Similarities | Belongs to the intercrine alpha (chemokine CxC) family. |
| Cellular Localization | Cell membrane. Secreted. Also exists as a soluble form. |
Storage & Handling
| Storage | Store at +4°C. Please refer to protocols. |