Anti-CTGF antibody - BSA and Azide free (Detector)

Overview

Product Type	Secreted Molecules
Host Species	Rabbit
Species Reactivity	Reacts with: Human
Application	Sandwich ELISA

Properties

Carrier Free	Yes
Purity	Protein A purified
Clonality	Monoclonal
Conjugate	Unconjugated
Isotype	IgG

Target

Function	Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Tissue Specificity	Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
Sequence Similarities	Belongs to the CCN family. Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 TSP type-1 domain. Contains 1 VWFC domain.
Cellular Localization	Secreted > extracellular space > extracellular matrix. Secreted.

Storage & Handling

Storage

Store at +4°C. Please refer to protocols.