Cat. No.: IBDAK-621816
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Product Type | Chemokines |
Host Species | Rabbit |
Species Reactivity | Reacts with: Human |
Application | Sandwich ELISA |
Properties
Carrier Free | Yes |
Clonality | Monoclonal |
Conjugate | Unconjugated |
Isotype | IgG |
Target
Function | Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. |
Tissue Specificity | Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine. |
Sequence Similarities | Belongs to the intercrine beta (chemokine CC) family. |
Cellular Localization | Secreted. |
Storage & Handling
Storage | Store at +4°C. Please refer to protocols. |