Cat. No.: IBDAK-621851
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Online InquiryOverview
Product Type | Macrophage / Inflamm. |
Host Species | Rabbit |
Species Reactivity | Reacts with: Human |
Application | Sandwich ELISA |
Properties
Carrier Free | Yes |
Purity | Protein A purified |
Clonality | Monoclonal |
Conjugate | Unconjugated |
Isotype | IgG |
Target
Function | Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed. |
Tissue Specificity | Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. |
Sequence Similarities | Belongs to the beta-defensin family. |
Cellular Localization | Secreted. |
Storage & Handling
Storage | Store at -20°C. Please refer to protocols. |