1,11b-Dihydro-11b-hydroxymedicarpin

Cat. No.: IBDI-430598

1,11b-Dihydro-11b-hydroxymedicarpin (11b-Hydroxy-11b,1-dihydromedicarpin) is a pterocarpan from Ononis viscosa subsp. breviflora is a Medicarpin derivative. Medicarpin, a natural pterocarpan, heals cortical bone defect by activation of Notch and Wnt canonical signaling pathways. Medicarpin prevents arthritis in post-menopausal conditions by arresting the expansion of TH17 cells and pro-inflammatory cytokines. Medicarpin down-regulates pro-inflammatory cytokines like TNF-α, IL-6 and IL-17A, while up-regulates anti-inflammatory cytokine IL-10 in arthritis (CIA) model of mice.

Product Details

Target	Interleukin Related
Molecular Weight	288.30
Synonyms	11b-Hydroxy-11b,1-dihydromedicarpin
SMILES	O=C(CC1)C=C2[[email protected]@]1(O)[[email protected]@](OC3=CC(OC)=CC=C34)([H])[[email protected]@]4([H])CO2
Structure Classification	Others

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.