The prevalence of glaucoma has gradually increased in recent years, and drug discovery and development efforts for the ocular field continue to be explored and advanced. As more new therapies are developed, the need for a broad range of glaucoma disease models has increased. In vivo or in vitro models that mimic the human glaucoma state can be utilized to validate a new therapeutic approach.
As a specialized glaucoma research company, Ace Therapeutics provides unique preclinical services in glaucoma research to researchers at academic institutions and pharmaceutical companies. Our services cover in vivo and in vitro studies to investigate the method of action and effect of drug candidates in the eye to identify effective treatments and therapeutic targets.
Services for Preclinical Research for Glaucoma
The use of in vitro systems to study glaucoma is an excellent strategy. Although in vitro models cannot mimic the complexity of glaucoma, they do provide new insights into the molecular mechanisms of glaucoma progression and therapy development in a faster and less expensive manner. Also, we need accurate in vitro ocular models to initially assess the safety of glaucoma drugs. We provide in vitro studies of cell-based models for glaucoma, exploring glaucoma-related molecular mechanisms in trabecular meshwork (TM), retinal ganglion cells (RGCs) and other cell types and in vitro characterization of anti-glaucoma drugs.
The success of the anti-glaucoma drug development pipeline depends on the success of basic and preclinical studies. In preclinical trials, we can perform in vivo studies in animal subjects. In vivo studies can demonstrate the effectiveness and safety of the drug on the body. Rodents, primates, rabbits, dogs, etc. are often used in preclinical in vivo studies and they often have the advantage of similar eye structure to humans and ease of handling. We offer clients a one-stop shop for preclinical in vivo studies, including the development of a range of animal models of glaucoma, evaluation of drug efficacy, safety, possible mechanisms of action, pharmacokinetic and pharmacodynamic properties.
Customized Preclinical Solutions
You may need pharmacology, toxicology and other studies to support your glaucoma eye preclinical studies. We understand the unique differences between ocular tissues and can offer our expertise in a variety of glaucoma disease areas.
- We have expertise in animal modeling, cell modeling that allows us to study a wide range of glaucoma states and test your novel drug in vivo or in vitro.
- We develop custom methods to assess the safety and tolerability of new therapeutics and materials with a high degree of accuracy. Understanding any potential adverse effects will guide your future experiments.
- We have comprehensive ophthalmic research capabilities, including ocular histopathology capabilities, ophthalmic microsurgery capabilities, and advanced imaging equipment capabilities.
Why Choose Our Services
- With years of experience in customizing animal models and cellular models, we have developed a series of various models for glaucoma and pharmacodynamic analysis services independently in several service projects.
- We have a team of professional ocular research technicians ready to assist you with your glaucoma research. The professional preclinical platform can provide a complete set of pharmacodynamic analysis services, including injection, sampling, analysis, molecular testing, etc.
You may need a specialized platform to support your preclinical glaucoma research. Working with Ace Therapeutics, you and your team have access to the full range of services and equipment we offer to meet any need for preclinical studies. Contact us and discover the difference we make. We can work together to find the best path forward for your glaucoma program.