Animal Models of Cardiovascular Diseases

Cardiovascular disease is currently one of the leading causes of death. In recent years, a series of advances have been made in research in the field of cardiovascular disease, but a large number of causal factors and pathological mechanisms remain to be explored. Therefore, Ace Therapeutics deeply understands the difficulties of the current research into cardiovascular disease, and is committed to providing animal model construction services, conventional genetically engineered animal models, and customized functional animal diets for the basic research and drug development of cardiovascular diseases.

The Significance of Animal Models in the Study of Cardiovascular Diseases

Advances in biomedical research often rely on the use of animal models as the experimental basis for both experimental and clinical hypotheses. Through the study of various diseases and life phenomena in animals, this has led to the advancement of human beings. With the deepening of research into the occurrence mechanism, prevention and therapy of human cardiovascular diseases, there is an urgent need to establish animal models that are simple, reproducible, have more typical pathological changes, are easy to evaluate and are suitable for intervention and therapy, so as to provide the necessary basis for the study of human cardiovascular diseases. Overall, animal model-based analyses have become almost indispensable in today's disease research and drug development processes. Therefore, the construction of appropriate experimental animal models of cardiovascular disease is essential to advance the study of cardiovascular disease mechanisms and therapies.

Fig. 1 Animal models for CMD in the presence of metabolic derangement. (Sorop O, et al., 2020)

Ace Therapeutics can provide custom development services for all types of animal models of cardiovascular disease, as well as genetically engineered mice with customized diets for special animal model needs.

Ace Therapeutics is dedicated to providing a wide range of specialized animal models to advance basic research, novel drug discovery and diagnostic method development for cardiovascular disease. If you are interested in our services, please don't hesitate to contact us.

1. Sorop, O.; et al. Experimental animal models of coronary microvascular dysfunction. Cardiovasc Res. 2020, 116(4):756-770.