Key Responsibilities:

• Provide timely feedback on problems encountered in experiments and seek solutions.
• Responsible for in vitro transcription and preparation and purification of mRNA in the pilot phase, as well as the development of mRNA transcription preparation process suitable for pilot scale up.
• Participate in the research of mRNA product delivery technology.
• Participate in pharmacological and toxicological studies of mRNA drugs.

Requirements:

• Ph.D. in pharmacology, molecular biology, bioengineering, organic chemistry, medicinal chemistry, or related discipline.
• Excellent teamwork and professionalism.
• Experience in vector construction and mRNA in vitro transcription.
• Extensive experience in nucleoside and nucleic acid synthesis and modification (base, backbone, glycocyclic) is preferred.