Products
-
- BBB DamageCell Death and ApoptosisNeuroinflammationNeuronal Damage and RepairOxidative StressVascular Mechanisms
- 3D BBB Models
- Organ-on-a-Chip BBB ModelsTranswell Models3D BBB Models Culture Substrate
- 3D HydrogelsCollagensAnmial BBB ModelsCell Lines for BBB Modeling
- Immortalized CellsPrimary CellsStem Cells
Fluorescent adenosine antagonist [XAC] (AC120)
Cat.#: ASSD-120
Specifications
Description Competitive fluorescent adenosine receptor antagonist (apparent KD values are 7.50, 7.37 and 7.30 for A2A, A3 and A1 respectively). Antagonizes the activity of NECA, an adenosine receptor agonist. Inhibits cAMP accumulation and stimulates inositol phosphate accumulation (pKb values are 6.4 and 6.5 respectively). Exhibits no intrinsic agonist activity. Synonyms Fluorescent Adenosine receptor Antagonist (A-633-AN), A-633-AN, XAC-X-BY630 Size 500 μg Applications For ligand binding; fluorescence imaging; high content analysis; kinetic analysis; cell sorting at adenosine A1 / A2A / A3 receptors use solutions up to 100 nM. Molecule Weight 974 Purity >97% Solubility Soluble in DMSO Form Purple solid Excitation 636 nm Emission 651 nm Storage Store at -20° C (protect from light) Shipping Shipped at 4°C Important We recommend briefly sonicating the sample when using to ensure it is fully dissolved and the solution is homogeneous. However, we do not recommend using the product after subjecting it to repetitive freeze-thaw cycles. Citation Guidance If you use our product in a scientific publication, please cite it as "Ace Therapeutics Cat.#". Click here to submit your paper's PubMed ID (PMID) to receive rewards. Related Products
Cat.# Name Size Price ASSD-121 Fluorescent adenosine A3 antagonist [XAC] (AC121) 500 μg inquiry ASSD-127 Fluorescent H3 antagonist [clobenpropit] (AC127) 50 μg inquiry ASSD-116 Annexin V-FITC Apoptosis Staining / Detection Kit (AC116) 1 kit, 100 tests inquiry ASSD-205 Acridinium C2 NHS Ester (AC205) 5 mg, 10 mg inquiry ASSD-222 Antifade Fluorescence Mounting Medium with Propidium Iodide (hard set) (AC222) 10 mL inquiry ASSD-224 Antifade Fluorescence Mounting Medium with DAPI (aqueous) (AC224) 10 mL inquiry ASSD-199 4,7-Dioxaoctylenediamine N-[(Cyanine 3) Monofunctional Hexanoic Acid]-N′-[2-fluoro-4′-phosphophenylacetic Acid] Diamide (AC199) 500 μg inquiry ASSD-108 Neutral Red Solution (0.33%) (AC108) 50 mL, 100 mL inquiry ASSD-119 Fluorescent adenosine agonist [NECA] (AC119) 500 μg inquiry ASSD-146 Pyronin Y (AC146) 1 g, 5g inquiry All of our products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
Ace Therapeutics is a global leading provider of stroke research services. We are committed to accelerating progress in stroke research and drug development.
0Inquiry Basket