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Fluorescent adenosine antagonist [XAC] (AC120)
Cat.#: ASSD-120
Specifications
Description Competitive fluorescent adenosine receptor antagonist (apparent KD values are 7.50, 7.37 and 7.30 for A2A, A3 and A1 respectively). Antagonizes the activity of NECA, an adenosine receptor agonist. Inhibits cAMP accumulation and stimulates inositol phosphate accumulation (pKb values are 6.4 and 6.5 respectively). Exhibits no intrinsic agonist activity. Synonyms Fluorescent Adenosine receptor Antagonist (A-633-AN), A-633-AN, XAC-X-BY630 Size 500 μg Applications For ligand binding; fluorescence imaging; high content analysis; kinetic analysis; cell sorting at adenosine A1 / A2A / A3 receptors use solutions up to 100 nM. Molecule Weight 974 Purity >97% Solubility Soluble in DMSO Form Purple solid Excitation 636 nm Emission 651 nm Storage Store at -20° C (protect from light) Shipping Shipped at 4°C Important We recommend briefly sonicating the sample when using to ensure it is fully dissolved and the solution is homogeneous. However, we do not recommend using the product after subjecting it to repetitive freeze-thaw cycles. Citation Guidance If you use our product in a scientific publication, please cite it as "Ace Therapeutics Cat.#". Click here to submit your paper's PubMed ID (PMID) to receive rewards. Related Products
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