Adenosine A1AR Affinity-Based Probe (AfBP) (AC139)

Cat.#: ASSD-139

ASSD-139

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Specifications


Description Adenosine A1AR Affinity-Based Probe (AfBP) incubate with live cells or membrane fractions can selectively label the desired receptor in the presence of other proteins. AfBP acts as a partial agonist which is highly specific to the A1AR and binds covalently. Apparent pKi values at A1AR are 7.8 and 9.5 (following a 4h preincubation), where a Ki shift indicates a covalent mode of action.
Size 50 μg
Applications For use in confocal microscopy, SDS-PAGE and chemical proteomics profiling applications.
Chemical Name 4-((3-((6-Amino-4-(benzo[d][1,3]dioxol-5-yl)-3,5-dicyanopyridin-2-yl)thio)propyl)(prop-2-yn-1-yl)carbamoyl)benzenesulfonyl fluoride
Molecule Weight 577.6
Molecular formula C27H20FN5O5S2
PubChem identifier 167312224
Purity >95%
Solubility Soluble in DMSO
Storage Store at -20° C
Shipping Shipped at 4°C

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All of our products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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